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Search Results to Fenghuang Zhan

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One or more keywords matched the following items that are connected to Zhan, Fenghuang

Item TypeName
Academic Article Toward the identification of distinct molecular and clinical entities of multiple myeloma using global gene expression profiling.
Academic Article The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma.
Academic Article Gene expression profiling and multiple myeloma.
Academic Article Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis.
Academic Article Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression.
Academic Article The distinct gene expression profiles of chronic lymphocytic leukemia and multiple myeloma suggest different anti-apoptotic mechanisms but predict only some differences in phenotype.
Academic Article High heparanase activity in multiple myeloma is associated with elevated microvessel density.
Academic Article Evaluation of multiple models to distinguish closely related forms of disease using DNA microarray data: an application to multiple myeloma.
Academic Article RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.
Academic Article Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma.
Academic Article Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.
Academic Article CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
Academic Article Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis.
Academic Article Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma.
Academic Article Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma.
Academic Article Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival.
Academic Article Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma.
Academic Article Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo.
Academic Article Gene expression profiling defines a high-risk entity of multiple myeloma.
Academic Article Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patients.
Academic Article The molecular classification of multiple myeloma.
Academic Article Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance.
Academic Article ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma.
Academic Article Low venous thromboembolic risk with bortezomib in multiple myeloma and potential protective effect with thalidomide/lenalidomide-based therapy: review of data from phase 3 trials and studies of novel combination regimens.
Academic Article Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation.
Academic Article Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma.
Academic Article NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.
Academic Article High-risk myeloma: a gene expression based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed disease treated with single-agent bortezomib or high-dose dexamethasone.
Academic Article CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma.
Academic Article Clinical, immunophenotypic, and genetic characterization of small lymphocyte-like plasma cell myeloma: a potential mimic of mature B-cell lymphoma.
Academic Article Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2.
Academic Article Mechanisms of thrombosis in paraproteinemias: the effects of immunomodulatory drugs.
Academic Article High expression of BCL3 in human myeloma cells is associated with increased proliferation and inferior prognosis.
Academic Article NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses.
Academic Article Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression.
Academic Article A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.
Academic Article The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells.
Academic Article Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells.
Academic Article A prospective evaluation of the biochemical, metabolic, hormonal and structural bone changes associated with bortezomib response in multiple myeloma patients.
Academic Article Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling.
Academic Article Survival effect of venous thromboembolism in patients with multiple myeloma treated with lenalidomide and high-dose dexamethasone.
Academic Article Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma.
Academic Article Activated protein C resistance as measured by residual factor V after Russell's viper venom and activated protein C treatment analyzed as a continuous variable in multiple myeloma and normal controls.
Academic Article Impact of bortezomib on bone health in myeloma: a review of current evidence.
Academic Article RARalpha2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma.
Academic Article Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells.
Academic Article An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma.
Academic Article High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients.
Academic Article Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma.
Academic Article Bone and paraproteinemias.
Concept Multiple Myeloma
Academic Article Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c-Myc in a model of plasma cell neoplasia.
Academic Article Expression of PAX5 in CD20-positive multiple myeloma assessed by immunohistochemistry and oligonucleotide microarray.
Academic Article Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib.
Academic Article CD27 is heterogeneously expressed in multiple myeloma: low CD27 expression in patients with high-risk disease.
Academic Article Smoldering multiple myeloma.
Academic Article Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts.
Academic Article Myeloma cell-derived Runx2 promotes myeloma progression in bone.
Academic Article Alteration of mitochondrial biogenesis promotes disease progression in multiple myeloma.
Academic Article Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.
Academic Article Prevention Is the Best Treatment: The Case for Understanding the Transition from Monoclonal Gammopathy of Undetermined Significance to Myeloma.
Academic Article Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma.
Academic Article Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma.
Academic Article CDKN1A and FANCD2 are potential oncotargets in Burkitt lymphoma and multiple myeloma.
Academic Article Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation.
Academic Article Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?
Academic Article Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus.
Academic Article NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase.
Academic Article VTD-melphalan is well tolerated and results in very high rates of stringent CR and MRD-negative status in multiple myeloma.
Academic Article Multiple Myeloma Tumor Cells are Selectively Killed by Pharmacologically-dosed Ascorbic Acid.
Academic Article RARa2 expression confers myeloma stem cell features.
Academic Article Preclinical validation of interleukin 6 as a therapeutic target in multiple myeloma.
Academic Article A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
Academic Article NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma.
Academic Article Nek2 is a novel regulator of B cell development and immunological response.
Academic Article Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma.
Academic Article Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome.
Academic Article NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.
Academic Article Identification and Characterization of Tumor-Initiating Cells in Multiple Myeloma.
Academic Article A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Academic Article Neoplastic plasma cell aberrant antigen expression patterns and their association with genetic abnormalities.
Academic Article Single-agent bortezomib or bortezomib-based regimens as consolidation therapy after autologous hematopoietic stem cell transplantation in multiple myeloma: a meta-analysis of randomized controlled trials.
Academic Article Ferroportin downregulation promotes cell proliferation by modulating the Nrf2-miR-17-5p axis in multiple myeloma.
Academic Article The impact of response kinetics for multiple myeloma in the era of novel agents.
Academic Article Early versus deferred treatment for smoldering multiple myeloma: a meta-analysis of randomized, controlled trials.
Academic Article Thalidomide treatment for patients with previously untreated multiple myeloma: a meta-analysis of randomized controlled trials.
Academic Article Serum high expression of miR-214 and miR-135b as novel predictor for myeloma bone disease development and prognosis.
Academic Article Chimeric antigen receptor T cell therapies for multiple myeloma.
Academic Article [Myeloma cancer stem cells:the new target for multiple myeloma].
Academic Article Downregulated miR-33b is a novel predictor associated with disease progression and poor prognosis in multiple myeloma.
Academic Article Chronic intermittent hypoxia enhances disease progression in myeloma-resistant mice.
Academic Article Carfilzomib enhances natural killer cell-mediated lysis of myeloma linked with decreasing expression of HLA class I.
Academic Article TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.
Academic Article Osteolytic disease in IL-6 and Myc dependent mouse model of human myeloma.
Academic Article Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model.
Academic Article Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma.
Academic Article Proteasome inhibitor lactacystin augments natural killer cell cytotoxicity of myeloma via downregulation of HLA class I.
Academic Article Bortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myeloma.
Academic Article Chromosome 1q21 gains confer inferior outcomes in multiple myeloma treated with bortezomib but copy number variation and percentage of plasma cells involved have no additional prognostic value.
Academic Article Myeloma cells resistance to NK cell lysis mainly involves an HLA class I-dependent mechanism.
Academic Article Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells.
Academic Article Lenalidomide after stem-cell transplantation for multiple myeloma: a meta-analysis of randomized controlled trials.
Academic Article Low serum miR-19a expression as a novel poor prognostic indicator in multiple myeloma.
Academic Article Copper-zinc superoxide dismutase-mediated redox regulation of bortezomib resistance in multiple myeloma.
Academic Article Secondary monoclonal gammopathy of undetermined significance is frequently associated with high response rate and superior survival in patients with plasma cell dyscrasias.
Academic Article Germline Risk Contribution to Genomic Instability in Multiple Myeloma.
Academic Article NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
Academic Article Polycomb-like Protein 3 Induces Proliferation and Drug Resistance in Multiple Myeloma and Is Regulated by miRNA-15a.
Grant Retinoid Based Treatment Approaches to Target the Myeloma Stem Cell
Grant NEK2 Over-expression Causes Drug Resistance in Myeloma
Academic Article RFWD2 induces cellular proliferation and selective proteasome inhibitor resistance by mediating P27 ubiquitination in multiple myeloma.
Academic Article Monitoring treatment response and disease progression in myeloma with circulating cell-free DNA.
Academic Article The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Academic Article Genetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression.
Academic Article HNRNPA2B1 promotes multiple myeloma progression by increasing AKT3 expression via m6A-dependent stabilization of ILF3 mRNA.
Academic Article PHF19 inhibition as a therapeutic target in multiple myeloma.
Academic Article Therapeutic effects of oligo-single-stranded DNA mimicking of hsa-miR-15a-5p on multiple myeloma.
Academic Article TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies.
Academic Article CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma.
Academic Article Laboratory Mice - A Driving Force in Immunopathology and Immunotherapy Studies of Human Multiple Myeloma.
Academic Article Epigenetic Deregulation of Telomere-Related Genes in Newly Diagnosed Multiple Myeloma Patients.
Academic Article WDR26 and MTF2 are therapeutic targets in multiple myeloma.
Academic Article FOXM1 regulates glycolysis and energy production in multiple myeloma.
Academic Article CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation.
Academic Article Concomitant deletion of the short arm (del(1p13.3)) and amplification or gain (1q21) of chromosome 1 by fluorescence in situ hybridization are associated with a poor clinical outcome in multiple myeloma.
Academic Article Variability of definition of high-risk multiple myeloma across phase III clinical trials.
Academic Article Risk of infections associated with the use of bispecific antibodies in multiple myeloma: a pooled analysis.
Academic Article Geographic and Racial Disparities in Access to Chimeric Antigen Receptor-T Cells and Bispecific Antibodies Trials for Multiple Myeloma.
Academic Article A gene signature can predict risk of MGUS progressing to multiple myeloma.
Academic Article Expression of integrin ?-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics.
Academic Article AKT supports the metabolic fitness of multiple myeloma cells by?restricting FOXO activity.
Academic Article Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma.
Academic Article BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions.
Academic Article High NEK2 expression in myeloid progenitors suppresses T?cell immunity in multiple myeloma.
Academic Article Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy.
Academic Article Transplant conditioning with bortezomib, thalidomide, and melphalan and intensive 2 year post-transplant therapy for multiple myeloma in older patients.
Academic Article Three years of maintenance with VRD in multiple myeloma: results of total therapy IIIB with a 15-year follow-up.
Academic Article Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth.
Academic Article Development and validation of an individualized and weighted Myeloma Prognostic Score System (MPSS) in patients with newly diagnosed multiple myeloma.
Academic Article Prognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems.
Academic Article Enhancing prognostic power in multiple myeloma using a plasma cell signature derived from single-cell RNA sequencing.

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  • Multiple Myeloma